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Fentanyl tablets were introduced in the mid-1990s for palliative use with the fentanyl patch. The following decade saw the introduction of fentanyl lozenges, orally disintegrating tablets, and sublingual sprays, which are absorbed through the skin in the mouth. Fentanyl tablets (also called fentanil) are a potent, synthetic analgesic with a rapid onset and short duration of action. It is a strong agonist at the μ-sodium receptors. Fentanyl is estimated to be 50 to 60 times more potent than morphine.

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Fentanyl powder is a potent synthetic opioid analgesic similar to morphine, but 50 to 60 times stronger. It is a Category II prescription drug and is typically used to treat patients with severe pain or to relieve pain following surgery. It is also occasionally used to treat patients with chronic pain who do not respond well to other opioids. In its pharmaceutical form, fentanyl is sold under names such as Actiq, Duragesic, and Sublimaze. Trade names for fentanyl or fentanyl-bound heroin include Apache, China Girl, China White, Dance Fever, Friend, Goodfella, Jackpot, Murder 8, TNT, and Tango and Cash.

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450.00
Gamma-hydroxybutyric acid or γ-hydroxybutyric acid (GHB), also known as 4-hydroxybutyric acid, is a naturally occurring neurotransmitter and a psychoactive drug. It is a precursor of GABA, glutamate, and glycine in certain brain regions. It acts on the GHB receptor and is a weak agonist at the GABA<sub>B</sub> receptor. GHB is used medically as a general anesthetic and to treat cataplexy, narcolepsy, and alcoholism. It is also used illegally as a recreational drug, to enhance athletic performance, as a date rape drug, and for recreational purposes.

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What is Ibrance (palbociclib) for?

Palbociclib is indicated for the treatment of postmenopausal women with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced breast cancer as initial endocrine-based therapy for their metastatic disease. It is indicated in combination with an aromatase inhibitor (hormone therapy) as initial endocrine-based therapy in postmenopausal women or with fulvestrant in women with disease progression after endocrine therapy.  

How does Ibrance (palbociclib) work?

 

Palbociclib is an inhibitor of cyclin-dependent kinase (CDK) 4 and 6.

Before a cell can divide, it must go through four phases. The first phase is a growth phase (G1 phase), the second a synthesis phase (S phase), the third another growth phase (G2 phase), and the final phase, in which the cell divides (M phase). Cancer cells divide extremely rapidly and pass through these four phases quickly. Palbociclib blocks the transition from the first G1 phase to the second S phase. This occurs by inhibiting cyclin-dependent kinases 4 and 6 (CDK4 and CDK6) – two proteins involved in entering the S phase [1] .

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Price range: €300.00 through €850.00
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In July 2009, the U.S. Drug Enforcement Agency (DEA) added JWH-018 to its list of controlled substances. Despite known cases of Spice seizures in Ohio and Florida, several states, including Alabama, Arkansas, Georgia, Kansas, Kentucky, North Dakota, and Tennessee, have implemented measures restricting the sale or possession of JWH-018. At least one case of JWH-018 addiction has been reported in the media. The patient took JWH-018 daily for several years. Withdrawal symptoms were more severe than those experienced with cannabis addiction. JWH-018, which is available for sale online, has been shown to cause significant changes in CB1 receptor density after administration, resulting in faster desensitization than with similar cannabinoids.

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The drug is a phenylacetylindole and acts as an agonist at the CB1 and CB2 receptors. It has a concentration of approximately 11 nM at CB1 and approximately 33 nM at CB2. JWH-250 came onto the market several years after its first written mention. The first discovery of it was made in May 2009 by German police, who found the drug in a herbal mixture intended for smoking. It was also found in powders and mixtures sold over the internet to researchers in Japan. These samples contained 77-165 mg per product. Due to the way it was sold, people most likely came into contact with JWH-250 without knowing it. Molar mass: 335.439 g/mol ChEMBL ID: 188031 ChemSpider ID: 23256117 PubChem CID: 44397540 Recipe: C22H25NO2

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Kadcyla (trastuzumab emtansine) is a cancer medicine used to treat advanced or metastatic HER2-positive breast cancer (cancer that has spread to other parts of the body) in adults who have previously received trastuzumab and a taxane.

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Price range: €200.00 through €1,350.00
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Ketamine is marketed under the brand name Ketalar. Ketalar is primarily used for gentle and long-lasting anesthesia. It is also used for pain relief and memory loss. Furthermore, it is used for chronic pain and for sedation during intensive treatment. Cardiac function, respiration, and respiratory reflexes generally remain intact during administration.

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Depression is the leading cause of intellectual disability worldwide and a major contributor to suicide rates. Ketamine is increasingly used as an effective treatment for depression due to its rapid onset of action. It works by binding to NMDA receptors in the brain and increasing the levels of the neurotransmitter glutamate.

Buy Keytruda (Pembrolizumab)

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Keytruda (pembrolizumab) is a medicine used to treat advanced melanoma, metastatic non-squamous NSCLC, recurrent or metastatic squamous cell carcinoma of the head and neck (HNSCC), recurrent classical Hodgkin lymphoma (cHL), locally advanced or metastatic urothelial carcinoma, solid tumors with the biomarkers MSI-H or dMMR, recurrent locally advanced or metastatic adenocarcinoma of the stomach or gastroesophageal junction, renal cell carcinoma, and triple-negative breast cancer.

Buy MDAI

Price range: €250.00 through €1,500.00
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MDAI and all other phenethylamines sold on this website are intended for research and scientific purposes. The test substance designated as MDAI is an active ingredient with potential physiological and psychoactive effects and has the formula C10H11NO2 HCl. Its molecular weight is 213.7 g/mol. Buy MDAI online. This substance is truly new, therefore the toxicological and physiological properties of MDAI are unknown. Phenethylamine derivatives such as 5,6-methylenedioxy-2-aminoindan may have stimulant and entactogenic properties. Buy MDAI online. 6,7-Dihydro-5H-indeno[5,6-d]-1,3-dioxol-6-amine, monohydrochloride and all other active ingredients sold on this site are intended for research and measurable applications. Please store this phenethylamine in a cool, dry place. The phenethylamine compound MDA.I is safe for up to 2 years under proper storage conditions. Buy MDA.I online.

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Price range: €280.00 through €1,800.00
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Methylenedioxymethamphetamine (MDMA) is a synthetic drug that alters mood and perception (attention to surrounding objects and conditions). Chemically similar to both stimulants and psychoactive substances, it produces feelings of heightened energy, euphoria, emotional warmth, and distorted physical and worldly perception. Originally popular in the nightclub scene and at all-night dance parties ("raves"), the drug now affects a wider range of people, who commonly refer to it as "raft" or "molly."